Issues associated with microarray data analysis and integration
نویسندگان
چکیده
1Cancer Genetics Branch, National Human Genome Research Institute, 49 Convent Drive, Bethesda, Maryland 20892 USA. 2Electrical Engineering Department, Texas A&M University, College Station, Texas 77843, USA. There are many statistical issues associated with the analysis and integration of microarray data. Here we touch on a few basic issues that relate to the current stage of the technology. Our perspective is that the data needs to be acquired, processed and analysed so as to facilitate pertinent and meaningful conclusions. Ultimately this requires suitable experimental design, appropriate mathematical modelling and valid statistical analysis. In Design and Analysis of Experiments1, Douglas Montgomery writes:
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